Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964539 | 1.00 | TSHR (0.77) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL25057031 | 0.94 | LMNA (0.76) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20964645 | 0.88 | LMNA (0.82) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20964680 | 0.88 | LMNA (0.82) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20964667 | 0.88 | NPC1 (0.68) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL19745442 | 0.87 | LMNA (1.00) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20964601 | 0.86 | LMNA (0.80) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20965291 | 0.85 | L3MBTL1 (0.55) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL25057030 | 0.84 | LMNA (0.73) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20965401 | 0.84 | LMNA (0.68) | TSHRLMNAALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034249-A1 | COMPOSITIONS AND METHODS FOR MODIFYING FERTILITY | THE BROAD INSTITUTE, INC. (US) | 2026-02-05 | — | — | US | disclosed |
| CN-116170338-A | Method and device for detecting open radio frequency unit, simulator and electronic equipment | 四川恒湾科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034249-A1 | COMPOSITIONS AND METHODS FOR MODIFYING FERTILITY | PGRMC2, TAGLN2, PGRMC1 | TSHR 4024/4885LMNA 1047/4885ALDH1A1 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.