Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964660 | 0.89 | SMN1; SMN2 (0.63) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL19744985 | 0.88 | SMN1; SMN2 (0.62) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL20964627 | 0.88 | LMNA (0.62) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL30428560 | 0.88 | TSHR (0.77) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL20964539 | 0.88 | TSHR (0.77) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL20965408 | 0.87 | L3MBTL1 (0.55) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL20965422 | 0.87 | SMN1; SMN2 (0.60) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL20964704 | 0.85 | SMN1; SMN2 (0.59) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL25057031 | 0.82 | LMNA (0.76) | NPC1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL20964609 | 0.81 | ALDH1A1 (0.61) | LMNATSHRSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20190127361-A1 | Therapeutic Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | SDHA, SLC10A1, SERPINC1 | NPC1 11/4885L3MBTL1 4755/4885LMNA 1413/4885 |
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | SERPINC1, F12, RPL35 | NPC1 2196/4885L3MBTL1 4517/4885LMNA 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.