Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366355 | 1.00 | UCHL1 (0.42) | UCHL1DDB1CRBNHSD11B1MEN1 | |
| SCHEMBL30207832 | 0.90 | HSD11B1 (0.41) | UCHL1DDB1CRBNHSD11B1MEN1 | |
| SCHEMBL19667491 | 0.90 | HSD11B1 (0.41) | UCHL1DDB1CRBNHSD11B1MEN1 | |
| SCHEMBL3697808 | 0.83 | PTPN1 (0.53) | UCHL1HSD11B1PTPN1 | |
| SCHEMBL21881601 | 0.83 | PTPN1 (0.53) | UCHL1HSD11B1PTPN1 | |
| SCHEMBL22319955 | 0.82 | DRD2 (0.41) | DRD2 | |
| SCHEMBL29376321 | 0.82 | NAMPT (0.48) | MEN1KMT2AMAPK1NAMPTDRD2 | |
| SCHEMBL12013723 | 0.82 | NAMPT (0.48) | MEN1KMT2AMAPK1NAMPTDRD2 | |
| SCHEMBL14138611 | 0.82 | NAMPT (0.48) | MEN1KMT2AMAPK1NAMPTDRD2 | |
| SCHEMBL24975552 | 0.81 | USP2 (0.41) | UCHL1DDB1CRBNMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11833162-B2 | Macrocyclic derivatives, process for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2023-12-05 | — | — | US | disclosed |
| CN-111511750-B | Macrocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2023-06-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11833162-B2 | Macrocyclic derivatives, process for preparing same and pharmaceutical compositions containing same | C1R, F12, RDX | UCHL1 3319/4885DDB1 4207/4885CRBN 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.