Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 7/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | KLRK1 | P26718 | 7/20 | 0.39 |
| ▸ | MICA | Q29983 | 7/20 | 0.39 |
| ▸ | RAET1L | Q5VY80 | 7/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.37 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.37 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.37 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.37 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.37 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.37 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237631 | 0.90 | SLC6A9 (0.48) | SLC6A9HSD17B2KLRK1MICARAET1L | |
| SCHEMBL3041062 | 0.90 | FLT1 (0.41) | SLC6A9KLRK1MICARAET1LCES2 | |
| SCHEMBL3262723 | 0.80 | SLC6A9 (0.42) | SLC6A9KMT2A | |
| SCHEMBL3239348 | 0.80 | KLRK1 (0.41) | SLC6A9KLRK1MICARAET1LSLC6A2 | |
| SCHEMBL3030679 | 0.79 | SLC6A2 (0.45) | SLC6A9KLRK1MICARAET1LSLC6A2 | |
| SCHEMBL3240099 | 0.77 | CRHR1 (0.46) | SLC6A9KLRK1MICARAET1LMEN1 | |
| SCHEMBL3237991 | 0.77 | SLC6A9 (0.40) | SLC6A9 | |
| SCHEMBL3037837 | 0.77 | SLC6A9 (0.47) | SLC6A9 | |
| SCHEMBL3239594 | 0.76 | KCNQ3 (0.44) | SLC6A9KLRK1MICARAET1L | |
| SCHEMBL1348675 | 0.76 | SLC6A9 (0.51) | SLC6A9HSD17B2KLRK1MICARAET1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216837-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | US | disclosed |
| US-20100216837-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | US | disclosed |
| US-20100216837-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216837-A1 | GLYCINE TRANSPORT INHIBITORS | SLC18A2, SLC6A5, SLC1A2 | SLC6A9 13/4885HSD17B2 1053/4885KLRK1 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.