Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.58 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 11/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781370 | 0.73 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL4929162 | 0.73 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL7103933 | 0.68 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL6786083 | 0.67 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL4510825 | 0.63 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL21187595 | 0.63 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL29697758 | 0.63 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL29987830 | 0.63 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL7098571 | 0.63 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL20572256 | 0.62 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312562-A1 | TETRAHYDRO-3H-PYRAZOLO QUINOLONE AND TETRAHYDRO-3H-PYRROLO[3,2-F]QUINOLINE -CONTAINING COMPOUNDS AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-10-05 | — | — | US | disclosed |
| EP-4175637-A2 | TETRAHYDRO-3H-PYRAZOLO QUINOLONE AND TETRAHYDRO-3H-PYRROLO[3,2-F]QUINOLINE-CONTAINING COMPOUNDS AND USES THEREOF | Purdue Research Foundation (US) | 2023-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312562-A1 | TETRAHYDRO-3H-PYRAZOLO QUINOLONE AND TETRAHYDRO-3H-PYRROLO[3,2-F]QUINOLINE -CONTAINING COMPOUNDS AND USES THEREOF | TUBB3, TUBA1C, TUBB1 | GRIA1 1716/4885GRIA2 1702/4885GRIA3 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.