Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11675997 | 0.84 | S1PR4 (0.58) | S1PR4LMNARAB9AALDH1A1CYP3A4 | |
| SCHEMBL12993940 | 0.83 | LMNA (0.51) | S1PR4LMNARAB9AALDH1A1CYP3A4 | |
| SCHEMBL11130878 | 0.81 | KYNU (0.37) | RAB9AALDH1A1GAAHPGDCA12 | |
| SCHEMBL30433135 | 0.80 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TDP1HTTALOX15 | |
| SCHEMBL11878546 | 0.79 | S1PR4 (0.50) | S1PR4LMNARAB9AALDH1A1CYP3A4 | |
| SCHEMBL4622820 | 0.77 | ALDH1A1 (0.56) | S1PR4LMNARAB9AALDH1A1CYP3A4 | |
| SCHEMBL9877591 | 0.77 | ALDH1A1 (0.49) | S1PR4LMNARAB9AALDH1A1CYP3A4 | |
| SCHEMBL9877593 | 0.77 | CA2 (0.51) | S1PR4LMNARAB9AALDH1A1CYP3A4 | |
| SCHEMBL11608207 | 0.76 | ALDH1A1 (0.57) | LMNAALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL392987 | 0.75 | CA2 (0.57) | S1PR4LMNARAB9AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431585-A | THIAZOLE AND THIOPHENE DYES; DIAZOTIZATION; COUPLING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-02-14 | — | — | US | disclosed |