Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211785 | 0.85 | PAM (0.48) | FFAR1FFAR4GAAKMT2AHRAS | |
| SCHEMBL5177626 | 0.79 | IDO1 (0.46) | TSHRRECQLGAAMEN1KMT2A | |
| SCHEMBL336981 | 0.76 | CA2 (0.47) | GAAMEN1KMT2AMAPTTDP1 | |
| Acetic Acid SCHEMBL21980115 | 0.76 | EPHX2 (0.53) | TSHRMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL8603268 | 0.75 | IDO1 (0.46) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5506614 | 0.75 | KDM4E (0.45) | MEN1KMT2AMAPTTDP1HRAS | |
| SCHEMBL12805042 | 0.75 | HRAS (0.42) | KEAP1GAAMEN1KMT2AMAPT | |
| SCHEMBL15103137 | 0.74 | IDO1 (0.50) | TSHRGAAMEN1KMT2AMAPT | |
| SCHEMBL21611670 | 0.73 | STING1 (0.54) | TSHRRECQLGAASMN1; SMN2MEN1 | |
| SCHEMBL27315456 | 0.73 | IDO1 (0.53) | RECQLGAASMN1; SMN2MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168198-A1 | Mitochondria-targeted antioxidant prodrugs and methods of use | UNIVERSITY OF ROCHESTER | 2010-07-01 | — | — | US | claimed |
| US-8470861-B2 | Mitochondria-targeted antioxidant prodrugs and methods of use | UNIVERSITY OF ROCHESTER (US) | 2013-06-25 | — | — | US | disclosed |
| US-20100168198-A1 | Mitochondria-targeted antioxidant prodrugs and methods of use | UNIVERSITY OF ROCHESTER | 2010-07-01 | — | — | US | disclosed |
| US-20090306125-A1 | Mitochondria-Targeted Antioxidant Prodrugs and Methods of Use | UNIVERSITY OF ROCHESTER | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306125-A1 | Mitochondria-Targeted Antioxidant Prodrugs and Methods of Use | TXNRD2, HADHA, PRDX5 | KEAP1 402/4885FFAR1 306/4885FFAR4 373/4885 |
| US-20100168198-A1 | Mitochondria-targeted antioxidant prodrugs and methods of use | TXNRD2, HADHA, PRDX5 | KEAP1 402/4885FFAR1 306/4885FFAR4 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.