Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.75 |
| ▸ | BCR | P11274 | 1/20 | 0.75 |
| ▸ | RELA | Q04206 | 3/20 | 0.74 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.56 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472138 | 1.00 | ABL1 (0.75) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL2947228 | 0.87 | NFE2L2 (0.71) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL2947227 | 0.87 | NFE2L2 (0.71) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL28476046 | 0.86 | ABL1 (0.64) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL28476047 | 0.86 | ABL1 (0.64) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL5492964 | 0.85 | RELA (1.00) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL5492969 | 0.85 | RELA (1.00) | ABL1ABCB1BCRRELANFE2L2 | |
| SCHEMBL700257 | 0.83 | NFE2L2 (0.76) | RELANFE2L2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL700256 | 0.83 | NFE2L2 (0.76) | RELANFE2L2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL17680678 | 0.83 | RELA (0.72) | ABL1ABCB1BCRRELANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848560-A | Preparation method of benzofuran derivative | 中国科学院成都生物研究所 | 2020-10-30 | — | — | CN | disclosed |
| WO-2010097811-A1 | MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | disclosed |
| US-20070276172-A1 | Single step microwave induced process for the preparation of substituted stilbenes and its analogs | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-11-29 | — | — | US | disclosed |
| WO-2007110883-A1 | A SINGLE STEP MICROWAVE INDUCED PROCESS FOR THE PREPARATION OF SUBSTITUTED STILBENES AND ITS ANALOGS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276172-A1 | Single step microwave induced process for the preparation of substituted stilbenes and its analogs | HRH3, HPD, TET2 | ABL1 1030/4885ABCB1 4716/4885BCR 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.