Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14270969 | 0.85 | KMT2A (0.42) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL30434788 | 0.82 | KMT2A (0.40) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL11183619 | 0.81 | KMT2A (0.39) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL28101592 | 0.73 | L3MBTL1 (0.36) | KMT2ARAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL30434613 | 0.72 | NPC1 (0.35) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL14294672 | 0.72 | CHRM2 (0.45) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL7918782 | 0.71 | KMT2A (0.52) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL28883975 | 0.68 | KMT2A (0.41) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL25083052 | 0.68 | PDE2A (0.41) | HPGDKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL31469535 | 0.67 | TDP1 (0.38) | KMT2ARAB9ASMN1; SMN2NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178286-B | N (N)2Alkyl substituted triazole derivative and synthetic method and application thereof | 华东师范大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-116178286-A | High-selectivity N 2 Alkyl substituted triazole derivative and synthetic method and application thereof | 华东师范大学 | 2023-05-30 | — | — | CN | disclosed |