Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27255898 | 0.78 | EP300 (0.44) | KIF11KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL13509095 | 0.75 | TDP1 (0.43) | KDM4EALDH1A1LMNAHPGDNFKB1 | |
| SCHEMBL13863837 | 0.71 | ALDH1A1 (0.55) | HTR2AHTR2CHTR2BKIF11ALDH1A1 | |
| SCHEMBL29078271 | 0.70 | CTSS (0.39) | PDE2AKIF11KDM4EALDH1A1LMNA | |
| SCHEMBL24949783 | 0.70 | TOP2A (0.36) | — | |
| SCHEMBL29009112 | 0.68 | CXCR2 (0.47) | KIF11LMNAEPHB4TEK | |
| SCHEMBL12377265 | 0.68 | PTGS2 (0.49) | PDE2APTGS2EPHB4TEK | |
| SCHEMBL14557164 | 0.67 | ALDH1A1 (0.46) | KIF11KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL2629316 | 0.67 | KEAP1 (0.58) | KIF11F2RL3PTGS2KCNH2EPHB4 | |
| SCHEMBL4089672 | 0.66 | TRPV3 (0.43) | PDE2AHTR2AHTR2CHTR2BPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4197333-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | Syngenta Crop Protection AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| WO-2023021020-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-23 | — | — | WO | disclosed |