Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.34 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30435192 | 0.85 | KMT2A (0.40) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30434788 | 0.85 | KMT2A (0.40) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11183619 | 0.84 | KMT2A (0.39) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL25083052 | 0.78 | PDE2A (0.41) | HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28101592 | 0.76 | L3MBTL1 (0.36) | KMT2ARAB9ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL30434613 | 0.75 | NPC1 (0.35) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14294672 | 0.74 | CHRM2 (0.45) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7918782 | 0.74 | KMT2A (0.52) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13222027 | 0.71 | RECQL (0.43) | KMT2AMEN1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL28883975 | 0.71 | KMT2A (0.41) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718600-B2 | 1,2,3-triazole inhibitors of P97 AAA ATPase activity | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2023-08-08 | — | — | US | disclosed |
| US-20080038225-A1 | TRIAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038225-A1 | TRIAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, SPINT2, CTSC | KMT2A 2796/4885MEN1 4318/4885RAB9A 3089/4885 |
| US-11718600-B2 | 1,2,3-triazole inhibitors of P97 AAA ATPase activity | ATAD3B, ATAD3A, PSMG3 | KMT2A 2849/4885MEN1 3629/4885RAB9A 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.