SCHEMBL30436298

SCHEMBL30436298

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)C(C)C)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FURIN P09958 6/20 0.52
PCSK6 P29122 1/20 0.52
CTSL P07711 1/20 0.43
ERAP2 Q6P179 1/20 0.43
ERAP1 Q9NZ08 1/20 0.43
LNPEP Q9UIQ6 1/20 0.43
PRSS1 P07477 2/20 0.41
NPY4R P50391 3/20 0.40
NPY1R P25929 2/20 0.40
NPY2R P49146 2/20 0.40
NPY5R Q15761 2/20 0.40
CTSB P07858 1/20 0.40
CTSK P43235 1/20 0.40
NMT2 O60551 1/20 0.39
NMT1 P30419 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31177108 0.85 DPP8 (0.44) ERAP2ERAP1LNPEPNMT2NMT1
SCHEMBL30688852 0.84 GRIN2D (0.44) FURINPCSK6CTSLGRIN2DGRIN3B
SCHEMBL31181199 0.84 ERAP2 (0.46) FURINPCSK6ERAP2ERAP1LNPEP
SCHEMBL10652275 0.84 NMT2 (0.43) FURINPCSK6ERAP2ERAP1LNPEP
SCHEMBL31369287 0.83 GRIN2D (0.44) FURINPCSK6ERAP2ERAP1LNPEP
SCHEMBL1711321 0.83 CPB2 (0.47) FURINPCSK6ERAP2ERAP1LNPEP
SCHEMBL1711738 0.83 CPB2 (0.47) FURINPCSK6ERAP2ERAP1LNPEP
SCHEMBL1711325 0.83 CPB2 (0.47) FURINPCSK6ERAP2ERAP1LNPEP
SCHEMBL30436626 0.83 NPY4R (0.48) FURINPCSK6ERAP2ERAP1LNPEP
SCHEMBL30509914 0.83 NPY4R (0.48) FURINPCSK6ERAP2ERAP1LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269321-B GLP-1 analogue fusion protein 鲁南制药集团股份有限公司 2023-05-12 CN disclosed