Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218192 | 0.81 | PTPN1 (0.49) | ALOX15SIRT1KMT2AMEN1MAOB | |
| SCHEMBL29853102 | 0.81 | PTPN1 (0.49) | ALOX15SIRT1KMT2AMEN1MAOB | |
| SCHEMBL2271953 | 0.79 | SIRT1 (0.50) | ALOX15SIRT1MCL1KMT2AMEN1 | |
| SCHEMBL9276705 | 0.73 | ALOX15 (0.79) | ALOX15MCL1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19627181 | 0.73 | ALOX15 (0.60) | ALOX15KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL742927 | 0.70 | PIM1 (0.55) | ALOX15KMT2AMEN1MAOBMAPT | |
| SCHEMBL27279621 | 0.70 | MAOB (0.49) | SIRT1KMT2AMAOBMAPTSMN1; SMN2 | |
| SCHEMBL9277642 | 0.70 | ALOX15 (0.56) | ALOX15KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL30595358 | 0.68 | SHBG (0.54) | ALOX15KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28472333 | 0.68 | SHBG (0.48) | ALOX15MCL1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253704-B | Paeoveitol D derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2024-11-26 | — | — | CN | claimed |
| CN-116253704-A | Paeovaitol D derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-06-13 | — | — | CN | claimed |
| CN-116253704-B | Paeoveitol D derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2024-11-26 | — | — | CN | disclosed |
| CN-116253704-B | Paeoveitol D derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2024-11-26 | — | — | CN | disclosed |
| CN-116253704-B | Paeoveitol D derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2024-11-26 | — | — | CN | disclosed |
| CN-116253704-A | Paeovaitol D derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-06-13 | — | — | CN | disclosed |
| CN-116253704-A | Paeovaitol D derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-06-13 | — | — | CN | disclosed |
| CN-116253704-A | Paeovaitol D derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-06-13 | — | — | CN | disclosed |