Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173634 | 1.00 | NPC1 (0.53) | NPC1RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL30337692 | 0.89 | METAP2 (0.45) | NPC1RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL8974216 | 0.89 | METAP2 (0.45) | NPC1RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL23253055 | 0.88 | NPC1 (0.49) | NPC1RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL6804411 | 0.87 | METAP2 (0.48) | NPC1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL30087143 | 0.87 | METAP2 (0.48) | NPC1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL2322693 | 0.82 | LDHA (0.55) | NPC1RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL16835778 | 0.80 | JAK2 (0.45) | NPC1RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL9237008 | 0.79 | KDM1A (0.57) | NPC1RXFP1MEN1KMT2AKDM4E | |
| SCHEMBL15614080 | 0.79 | HSD17B10 (0.56) | NPC1MEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630030-B | Novel benzamide derivatives as PPAR-gamma modulators | 梅迪比奥法尔玛公司 | 2023-06-20 | — | — | CN | disclosed |