SCHEMBL6804411

SCHEMBL6804411

Nc1ccc(-c2ccc(N)cn2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
ALDH1A1 P00352 4/20 0.48
MAPT P10636 4/20 0.48
TP53 P04637 3/20 0.48
HPGD P15428 3/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
HSD17B10 Q99714 3/20 0.48
KDM4E B2RXH2 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CYP3A4 P08684 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
GMNN O75496 1/20 0.44
PKM P14618 1/20 0.44
THPO P40225 1/20 0.44
BLM P54132 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30087143 1.00 METAP2 (0.48) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL8974216 0.97 METAP2 (0.45) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL30337692 0.97 METAP2 (0.45) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL22579291 0.88 ALDH1A1 (0.58) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL29424406 0.88 ALDH1A1 (0.58) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL18573201 0.87 NPC1 (0.49) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL13192068 0.87 KDM1A (0.57) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL9237008 0.87 KDM1A (0.57) METAP2MEN1KMT2AALDH1A1MAPT
SCHEMBL3173634 0.87 NPC1 (0.53) METAP2MEN1KMT2AALDH1A1NPC1
SCHEMBL15614080 0.87 HSD17B10 (0.56) MEN1KMT2AALDH1A1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113774509-B Method and device for preparing modified meta-aramid fiber through continuous polymerization-dry-wet spinning 株洲时代新材料科技股份有限公司 2022-09-13 CN claimed
CN-114957661-A Preparation method of display screen cover plate, display screen cover plate and display device 京东方科技集团股份有限公司 2022-08-30 CN claimed
CN-108346766-A A kind of heat-staple lithium ion battery separator and preparation method thereof 长沙新材料产业研究院有限公司 2018-07-31 CN claimed
CN-107189436-A A kind of polyimide nano foam and preparation method thereof 中国科学院长春应用化学研究所 2017-09-22 CN claimed
CN-116635365-A Material for electronic devices 默克专利有限公司 2023-08-22 CN disclosed
CN-110475838-B Polymer for liquid crystal aligning agent, liquid crystal aligning agent composition comprising same, liquid crystal aligning film using same, and liquid crystal display device 株式会社LG化学 2023-05-26 CN disclosed
CN-112898198-B Nitrogen-containing aromatic heterocyclic nitro compound and preparation method and application thereof 中国科学院长春应用化学研究所 2023-04-07 CN disclosed
CN-110753739-B Liquid crystal aligning agent composition, method for preparing liquid crystal alignment film using the same, and liquid crystal alignment film and liquid crystal display using the same 株式会社LG化学 2023-03-14 CN disclosed
CN-110191938-B Liquid crystal aligning agent composition, method for preparing liquid crystal alignment film using the same, and liquid crystal alignment film using the same 株式会社LG化学 2023-03-10 CN disclosed
CN-110546238-B Liquid crystal aligning agent composition, method for preparing liquid crystal alignment film using the same, and liquid crystal alignment film using the same 株式会社LG化学 2023-02-21 CN disclosed
CN-110546239-B Copolymer for liquid crystal aligning agent, liquid crystal aligning agent comprising same, and liquid crystal alignment film and liquid crystal display device using same 株式会社LG化学 2023-02-17 CN disclosed
CN-110168054-B Polymer for liquid crystal aligning agent, liquid crystal aligning agent comprising same, and liquid crystal alignment film and liquid crystal display device using same 株式会社LG化学 2023-02-17 CN disclosed
WO-2019039791-A1 POLYMER FOR LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNING AGENT COMPOSITION COMPRISING SAME, AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME COMPOSITION 주식회사 엘지화학 2019-02-28 WO disclosed
CN-108558770-A A kind of preparation method of diamino azaaromatics 中国科学院长春应用化学研究所 2018-09-21 CN disclosed
CN-108346766-A A kind of heat-staple lithium ion battery separator and preparation method thereof 长沙新材料产业研究院有限公司 2018-07-31 CN disclosed
CN-107189436-A A kind of polyimide nano foam and preparation method thereof 中国科学院长春应用化学研究所 2017-09-22 CN disclosed
US-6794378-B2 ANTIINFLAMMATORY AGENTS AJINOMOTO CO., INC. (JP) 2004-09-21 US disclosed
CN-1372548-A Heterocyclic compound and medical use thereof AJINOMOTO KK (JP) 2002-10-02 CN disclosed
US-20020133005-A1 Heterocyclic compounds and medical use thereof AJINOMOTO CO., INC. (JP) 2002-09-19 US disclosed
EP-1193255-A1 HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF Ajinomoto Co., Inc. (JP) 2002-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133005-A1 Heterocyclic compounds and medical use thereof NFKBIA, CHUK, RELA METAP2 1266/4885MEN1 3117/4885KMT2A 3137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.