SCHEMBL30437331

SCHEMBL30437331

COc1nc(Cl)ccc1C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.66
POLB P06746 1/20 0.66
RAB9A P51151 2/20 0.42
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42
TUBA3E Q6PEY2 1/20 0.42
TUBA1A Q71U36 1/20 0.42
TUBA1C Q9BQE3 1/20 0.42
TUBB6 Q9BUF5 1/20 0.42
TUBB2B Q9BVA1 1/20 0.42
TUBB1 Q9H4B7 1/20 0.42
NPC1 O15118 1/20 0.42
GABRP O00591 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6742273 1.00 TDP1 (0.66) TDP1POLBRAB9ATUBB4ATUBB
SCHEMBL20719247 0.85 POLB (0.47) TDP1POLBRAB9ATUBB4ATUBB
SCHEMBL11607437 0.85 POLB (0.47) TDP1POLBRAB9ATUBB4ATUBB
SCHEMBL29361411 0.84 NNMT (0.49) TDP1POLBRAB9ATUBB4ATUBB
SCHEMBL31444462 0.84 TUBB4A (0.55) TDP1POLBRAB9ATUBB4ATUBB
SCHEMBL426830 0.84 TUBB4A (0.55) TDP1POLBRAB9ATUBB4ATUBB
SCHEMBL2527039 0.84 NNMT (0.49) TDP1POLBRAB9ATUBB4ATUBB
SCHEMBL20719057 0.82 TDP1 (0.45) TDP1POLBRAB9ATUBB4ATUBB
SCHEMBL6377769 0.82 MAPT (0.49) TDP1POLBRAB9ANPC1HPGD
SCHEMBL15647036 0.81 RAB9A (0.49) TDP1POLBRAB9ATUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
CN-116253678-A Method for rapidly preparing 2, 6-dichloropyridine-3-carboxylic acid based on micro-channel continuous flow technology 都创(重庆)药业有限公司 2023-06-13 CN disclosed