Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 4/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 4/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 4/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 4/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567033 | 0.78 | CA12 (0.53) | MEN1KMT2AMAPTHTTGALR3 | |
| SCHEMBL2801565 | 0.76 | MAPT (0.41) | MAPTSMN1; SMN2 | |
| SCHEMBL13218574 | 0.75 | RCE1 (0.47) | MEN1KMT2AMAPT | |
| SCHEMBL20308929 | 0.74 | CCNE2 (0.33) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL20308925 | 0.74 | TP53 (0.36) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL19672991 | 0.72 | CYP3A4 (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL19672933 | 0.72 | SOS1 (0.41) | MEN1KMT2AMAPTHTTEGFR | |
| SCHEMBL20308908 | 0.72 | SOS1 (0.41) | MEN1KMT2AMAPTHTTEGFR | |
| SCHEMBL11848196 | 0.71 | ALDH1A1 (0.58) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL31243247 | 0.71 | ALDH1A1 (0.58) | MEN1KMT2AMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253648-A | Synthesis method of aromatic amine compound without metal participation | 西安交通大学 | 2023-06-13 | — | — | CN | disclosed |