Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320159 | 0.71 | ALDH1A1 (0.37) | KDM4EHSD17B10ALDH1A1LMNAGAA | |
| SCHEMBL3833766 | 0.70 | ALDH1A1 (0.38) | KDM4EHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL12842030 | 0.67 | MAPK1 (0.42) | KDM5AKDM4CKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL12842048 | 0.66 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1LMNAMAPK1 | |
| SCHEMBL18662176 | 0.64 | GAA (0.35) | KDM5AKDM4CKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3234617 | 0.62 | MEN1 (0.46) | KDM5AKDM4CKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9884987 | 0.62 | ADORA2A (0.47) | KDM5AKDM4CKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL22291169 | 0.61 | MEN1 (0.34) | KDM5AKDM4CKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2467905 | 0.61 | KDM4E (0.50) | KDM5AKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL21610059 | 0.61 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167119-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | Bugworks Research, Inc. | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167119-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | ADORA2A, ADORA2B, ADORA1 | KDM5A 3169/4885KDM4C 4508/4885KDM4E 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.