SCHEMBL3833766

SCHEMBL3833766

Cc1cn2nc(C)c(N)c2nc1N

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30437587 0.70 KDM5A (0.36) ALDH1A1HSD17B10SMN1; SMN2KDM4E
SCHEMBL1833602 0.69 SMPD3 (0.49) ALDH1A1HPGDHSD17B10
SCHEMBL7465828 0.69 SMN1; SMN2 (0.41) ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E
SCHEMBL1833600 0.69 NOS3 (0.38) ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E
SCHEMBL28949476 0.69 ALDH1A1 (0.41) ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E
SCHEMBL21166828 0.68 ALDH1A1 (0.38) ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL7826142 0.68 MAPT (0.41) ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E
SCHEMBL38666602 0.67 RAB9A (0.46) ALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL3469124 0.65 PDE10A (0.43) ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E
SCHEMBL30320159 0.65 ALDH1A1 (0.37) ALDH1A1HPGDHSD17B10SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3474815-A1 PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION L'OREAL (FR) 2019-05-01 EP disclosed
WO-2017220676-A1 PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION L'OREAL (FR) 2017-12-28 WO disclosed
EP-1762223-B1 Composition for dyeing keratin fibres comprising at least one oxidation base and a particular polyoxyethylenated sorbitan ester ORÉAL L (FR) 2016-04-13 EP disclosed
EP-2065073-B1 Composition for the oxidation dyeing of keratin fibres comprising a cellulose with hydrophobic substituents, an oxidation dye and a long-chain fatty alcohol ORÉAL L (FR) 2015-08-19 EP disclosed
EP-2065074-B1 Composition for the oxidation dyeing of keratin fibres comprising a cellulose with hydrophobic substituent(s), an oxidation dye and a cationic polymer ORÉAL L (FR) 2014-06-18 EP disclosed
EP-1762222-B2 Process for colouring keratin fibres comprising a step of treating the scalp with a particular sorbitan ester OREAL (FR) 2013-08-21 EP disclosed
EP-1762222-B1 Process for colouring keratin fibres comprising a step of treating the scalp with a particular sorbitan ester OREAL (FR) 2009-10-07 EP disclosed
EP-2065073-A2 Composition for the oxidation dyeing of keratin fibres comprising a cellulose with hydrophobic substituents, an oxidation dye and a long-chain fatty alcohol L'Oréal (FR) 2009-06-03 EP disclosed
EP-2065074-A2 Composition for the oxidation dyeing of keratin fibres comprising a cellulose with hydrophobic substituent(s), an oxidation dye and a cationic polymer L'Oréal (FR) 2009-06-03 EP disclosed
EP-1879547-A1 DYEING COMPOSITION COMPRISING A DYE AND A PROPYLENE GLYCOL DERIVATIVE L'Oréal (FR) 2008-01-23 EP disclosed
EP-1762223-A1 Composition for dyeing keratin fibres comprising at least one oxidation base and a particular polyoxyethylenated sorbitan ester L'Oréal (FR) 2007-03-14 EP disclosed
EP-1762222-A1 Process for colouring keratin fibres comprising a step of treating the scalp with a particular sorbitan ester L'Oréal (FR) 2007-03-14 EP disclosed
WO-2006114529-A1 DYEING COMPOSITION COMPRISING A DYE AND A PROPYLENE GLYCOL DERIVATIVE L'OREAL (FR) 2006-11-02 WO disclosed