Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747828 | 0.82 | NPC1 (0.64) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL30437926 | 0.82 | NPC1 (0.64) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL3655341 | 0.79 | MGAM (0.54) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL29289908 | 0.78 | KDM4E (0.50) | KMT2ASCN9AKDM4ELMNAHTR2C | |
| SCHEMBL1839801 | 0.78 | LMNA (0.64) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL29289659 | 0.77 | CYP1A2 (0.48) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL29289913 | 0.76 | HTR2C (0.44) | NPC1RAB9ASCN9AHTR2C | |
| SCHEMBL29044143 | 0.74 | MEN1 (0.66) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL4097521 | 0.74 | ALDH1A1 (0.76) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL634452 | 0.73 | NAMPT (0.56) | RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | claimed |