SCHEMBL747828

SCHEMBL747828

CCN(C)C(=O)c1ccc2ccccc2n1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.64
RAB9A P51151 2/20 0.62
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
MGAM O43451 1/20 0.54
GAA P10253 2/20 0.53
ALDH1A1 P00352 2/20 0.53
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
CNR2 P34972 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
KDM4E B2RXH2 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HDAC8 Q9BY41 1/20 0.50
HPGD P15428 1/20 0.48
KDM4C Q9H3R0 1/20 0.48
OPRM1 P35372 1/20 0.47
OPRK1 P41145 1/20 0.47
TMEM97 Q5BJF2 1/20 0.47
SIGMAR1 Q99720 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30437926 1.00 NPC1 (0.64) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL29044143 0.85 MEN1 (0.66) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL1839801 0.83 LMNA (0.64) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL30438192 0.82 ALDH1A1 (0.60) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL10264501 0.80 NPC1 (0.53) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL28501492 0.78 MEN1 (0.58) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL14883267 0.77 MGAM (0.59) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL3655341 0.77 MGAM (0.54) NPC1RAB9AMEN1KMT2AMGAM
SCHEMBL28020587 0.77 MEN1 (0.47) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL12678009 0.77 P2RX7 (0.53) NPC1RAB9AMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4894409-A BLEND OR AMINO GROUP CONTAINING DIENE POLYMER AND SILICA FILLER NONCRACKING, WEAR RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-01-16 US claimed
US-4616069-A REACTING THE ALKALI METAL OR ALKALINE EARTH METAL TERMINATED POLYMER WITH TIN COMPOUND AND ORGANIC COMPOUND HAVING AMIDE OR THIOAMIDE LINKAGES NIPPON ZEON CO., LTD. (JP) 1986-10-07 US claimed
EP-3778654-B1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER ZEON CORP (JP) 2025-02-26 EP disclosed
US-11873364-B2 Method for producing conjugated diene rubber ZEON CORPORATION (JP) 2024-01-16 US disclosed
CN-111868098-B Method for producing conjugated diene rubber 日本瑞翁株式会社 2022-12-23 CN disclosed
EP-3778654-A1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER Zeon Corporation (JP) 2021-02-17 EP disclosed
US-20210017321-A1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER ZEON CORPORATION (JP) 2021-01-21 US disclosed
CN-111868098-A Method for producing conjugated diene rubber 日本瑞翁株式会社 2020-10-30 CN disclosed
CN-108203487-B Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer, method for synthesizing same, rubber composition, and tire 奇美实业股份有限公司 2020-07-14 CN disclosed
WO-2019189204-A1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER 日本ゼオン株式会社 2019-10-03 WO disclosed
CN-108203487-A Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer, method for synthesizing same, rubber composition, and tire 奇美实业股份有限公司 2018-06-26 CN disclosed
US-5463004-A Catalytic copolymerization with aromatic vinyl monomer with metal-secondary amine initiator BRIDGESTONE CORPORATION (JP) 1995-10-31 US disclosed
US-5463003-A Catalytic copolymerization with aromatic vinyl monomer with metal-secondary amine initiator BRIDGESTONE CORPORATION (JP) 1995-10-31 US disclosed
EP-0617060-A2 A rubber composition containing a conjugated diene polymer Bridgestone Corporation (JP) 1994-09-28 EP disclosed
EP-0572792-A1 Tire tread composition BRIDGESTONE CORPORATION (JP) 1993-12-08 EP disclosed
US-5248722-A Functionalized elastomer, oxidized carbon black, reduced hysteresis BRIDGESTONE CORPORATION (JP) 1993-09-28 US disclosed
US-4894409-A BLEND OR AMINO GROUP CONTAINING DIENE POLYMER AND SILICA FILLER NONCRACKING, WEAR RESISTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-01-16 US disclosed
EP-0180141-B1 PROCESS FOR MAKING DIENE POLYMER RUBBERS NIPPON ZEON CO., LTD. (JP) 1989-08-30 EP disclosed
US-4616069-A REACTING THE ALKALI METAL OR ALKALINE EARTH METAL TERMINATED POLYMER WITH TIN COMPOUND AND ORGANIC COMPOUND HAVING AMIDE OR THIOAMIDE LINKAGES NIPPON ZEON CO., LTD. (JP) 1986-10-07 US disclosed
EP-0180141-A1 Process for making diene polymer rubbers NIPPON ZEON CO., LTD. (JP) 1986-05-07 EP disclosed