Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 12/20 | 0.41 |
| ▸ | MTOR | P42345 | 10/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701931 | 1.00 | PIK3CA (0.41) | PIK3CAMTORFLT3AKT1L3MBTL1 | |
| SCHEMBL25703348 | 0.92 | SCN1A (0.35) | PIK3CAMTORALOX5APFEN1SCN1A | |
| SCHEMBL30438540 | 0.92 | SCN1A (0.35) | PIK3CAMTORALOX5APFEN1SCN1A | |
| SCHEMBL31529527 | 0.90 | ALDH1A1 (0.37) | PIK3CAMTORALOX5APFEN1SCN1A | |
| SCHEMBL25437180 | 0.86 | PIK3CA (0.40) | PIK3CAMTORFLT3AKT1L3MBTL1 | |
| SCHEMBL31529481 | 0.86 | PIK3CA (0.40) | PIK3CAMTORFLT3AKT1L3MBTL1 | |
| SCHEMBL25435602 | 0.77 | ALDH1A1 (0.37) | PIK3CAL3MBTL1ALOX5APFEN1SCN1A | |
| SCHEMBL25435598 | 0.77 | ALDH1A1 (0.37) | PIK3CAL3MBTL1ALOX5APFEN1SCN1A | |
| SCHEMBL30438543 | 0.75 | BRAF (0.36) | PIK3CAMTORAKT1L3MBTL1ALOX5AP | |
| SCHEMBL25702691 | 0.75 | BRAF (0.36) | PIK3CAMTORAKT1L3MBTL1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436955-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | Lario Therapeutics Limited (GB) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |