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SCHEMBL30438697

SCHEMBL30438697

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](N)CO)[C@@H](C)O)[C@@H](C)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 5/20 0.46
▸ OPRD1 P41143 5/20 0.46
▸ OPRK1 P41145 3/20 0.45
▸ GLP1R P43220 3/20 0.42
▸ SCTR P47872 1/20 0.42
▸ PRMT1 Q99873 1/20 0.42
▸ CALCR P30988 7/20 0.41
▸ RAMP3 O60896 3/20 0.41
▸ GRPR P30550 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30360222 0.94 OPRM1 (0.47) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30360225 0.94 OPRM1 (0.45) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30439513 0.94 OPRM1 (0.43) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30541188 0.92 GRPR (0.43) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30360223 0.91 OPRM1 (0.45) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL30712882 0.88 OPRM1 (0.59) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL29597233 0.85 OPRM1 (0.56) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL29597500 0.85 OPRM1 (0.56) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL31757234 0.84 OPRD1 (0.42) OPRM1OPRD1OPRK1GLP1RSCTR
SCHEMBL31168868 0.84 OPRM1 (0.43) OPRM1OPRD1OPRK1GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209459-A IL-10 muteins and fusion proteins thereof 美国安进公司 2023-06-02 — — CN disclosed
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