SCHEMBL30360222

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	4/20	0.47

▸	OPRD1	P41143	4/20	0.47

▸	GLP1R	P43220	6/20	0.45

▸	OPRK1	P41145	2/20	0.45

▸	SCTR	P47872	1/20	0.45

▸	KEAP1	Q14145	1/20	0.42

▸	CALCR	P30988	4/20	0.42

▸	GCGR	P47871	1/20	0.41

▸	GRPR	P30550	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30438697	0.94	OPRM1 (0.46)	OPRM1OPRD1GLP1ROPRK1SCTR
SCHEMBL30541188	0.92	GRPR (0.43)	OPRM1OPRD1GLP1ROPRK1SCTR
SCHEMBL30360225	0.91	OPRM1 (0.45)	OPRM1OPRD1GLP1ROPRK1SCTR
SCHEMBL30360223	0.91	OPRM1 (0.45)	OPRM1OPRD1GLP1ROPRK1SCTR
SCHEMBL30439513	0.89	OPRM1 (0.43)	OPRM1OPRD1GLP1ROPRK1SCTR
SCHEMBL30712882	0.87	OPRM1 (0.59)	OPRM1OPRD1GLP1ROPRK1SCTR
SCHEMBL10766959	0.84	OPRD1 (0.44)	OPRM1OPRD1GLP1ROPRK1SCTR
SCHEMBL10766953	0.84	OPRD1 (0.44)	OPRM1OPRD1GLP1ROPRK1SCTR
SCHEMBL30974284	0.84	GLP1R (0.46)	OPRM1OPRD1GLP1RSCTRKEAP1
SCHEMBL30032557	0.84	CTSB (0.44)	OPRM1OPRD1OPRK1GRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4172184-A2	IL-10 MUTEINS AND FUSION PROTEINS THEREOF	Amgen Inc. (US)	2023-05-03	—	—	EP	disclosed