Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768145 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19464250 | 0.85 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19463668 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19463978 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL20768143 | 0.83 | MAPT (0.43) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19463512 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19464067 | 0.80 | MAPT (0.42) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL28629447 | 0.72 | DHODH (0.38) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL28623585 | 0.72 | DHODH (0.38) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL22461525 | 0.70 | CSNK1D (0.58) | KDM4EALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |