Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629447 | 0.89 | DHODH (0.38) | DHODHBRS3PIK3CDPIK3CGALDH1A1 | |
| SCHEMBL19463318 | 0.88 | DHODH (0.37) | DHODHBRS3ALDH1A1KDM4EHPGD | |
| SCHEMBL19463668 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28615710 | 0.83 | BRS3 (0.35) | DHODHBRS3ALDH1A1KDM4EHPGD | |
| SCHEMBL24455511 | 0.80 | MAPT (0.42) | DHODHALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28619820 | 0.80 | MAPT (0.38) | DHODHALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28620031 | 0.77 | DCLRE1B (0.43) | DHODHALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20768145 | 0.72 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL30439174 | 0.72 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL20782378 | 0.71 | MAPT (0.44) | ALDH1A1KDM4EHPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |