Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439444 | 0.88 | MMP13 (0.43) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL30438737 | 0.81 | CNR1 (0.45) | MMP13MMP1MMP9CNR1ROCK2 | |
| SCHEMBL30439166 | 0.79 | MMP1 (0.47) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL23795306 | 0.79 | CNR1 (0.44) | MMP13MMP1MMP9CNR1ROCK2 | |
| SCHEMBL30439348 | 0.79 | CNR1 (0.44) | MMP13MMP1MMP9CNR1ROCK2 | |
| SCHEMBL24177978 | 0.79 | CNR1 (0.44) | MMP13MMP1MMP9CNR1ROCK2 | |
| SCHEMBL23795367 | 0.77 | PRKD3 (0.56) | CNR1ROCK2ROCK1 | |
| SCHEMBL24178114 | 0.77 | PRKD3 (0.56) | CNR1ROCK2ROCK1 | |
| SCHEMBL30439149 | 0.76 | MMP1 (0.45) | MMP13MMP1MMP9HTR6ADAM17 | |
| SCHEMBL23795348 | 0.76 | ROCK2 (0.45) | MMP13MMP1MMP9CNR1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116555-B | Rho kinase inhibitor and preparation method and application thereof | 北京盈科瑞创新药物研究有限公司 | 2023-06-02 | — | — | CN | disclosed |