Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30159413 | 0.94 | FAAH (0.45) | FAAHCES2CES1KMT2ASOAT1 | |
| SCHEMBL28721888 | 0.94 | FAAH (0.54) | FAAHCES2CES1KMT2AMEN1 | |
| SCHEMBL28907900 | 0.84 | CES2 (0.55) | FAAHCES2CES1KMT2ASOAT1 | |
| SCHEMBL125606 | 0.83 | KMT2A (0.48) | FAAHKMT2ASOAT1MEN1TP53 | |
| SCHEMBL21373849 | 0.80 | FAAH (0.41) | FAAHCES2CES1KMT2ASOAT1 | |
| SCHEMBL1367098 | 0.80 | FAAH (0.73) | FAAHCES2CES1KMT2AMEN1 | |
| SCHEMBL25293609 | 0.79 | KMT2A (0.52) | FAAHCES2CES1KMT2ASOAT1 | |
| SCHEMBL42735 | 0.79 | KMT2A (0.52) | FAAHCES2CES1KMT2ASOAT1 | |
| SCHEMBL15007818 | 0.79 | KMT2A (0.52) | FAAHCES2CES1KMT2ASOAT1 | |
| SCHEMBL25288050 | 0.79 | KMT2A (0.52) | FAAHCES2CES1KMT2ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | claimed |