Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688235 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AKDM4EMAPTLMNA | |
| SCHEMBL31727125 | 0.93 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9AKDM4EMAPTLMNA | |
| SCHEMBL856333 | 0.80 | TLR9 (0.52) | MAPTMEN1KMT2ASIRT2SIRT1 | |
| SCHEMBL28167164 | 0.79 | SIRT2 (0.41) | SMN1; SMN2RAB9AKDM4EMAPTLMNA | |
| SCHEMBL28841040 | 0.77 | ADRB1 (0.53) | MAPTMEN1KMT2AHTR6DRD2 | |
| SCHEMBL20995833 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9AKDM4EMAPTLMNA | |
| SCHEMBL21047718 | 0.76 | BCHE (0.42) | SMN1; SMN2RAB9AKDM4EMAPTLMNA | |
| SCHEMBL29117052 | 0.76 | RAB9A (0.54) | SMN1; SMN2RAB9AKDM4EMAPTLMNA | |
| SCHEMBL21047574 | 0.73 | CYP2A6 (0.41) | SMN1; SMN2RAB9AKDM4EMAPTLMNA | |
| SCHEMBL3060875 | 0.73 | KMT2A (0.47) | KMT2APIM1PRKCQGPR84DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702175-B | Preparation method of indole-3-succinimide | UNIV DONGHUA | 2014-08-13 | — | — | CN | claimed |
| CN-102702175-A | Preparation method of indole-3-succinimide | UNIV DONGHUA | 2012-10-03 | — | — | CN | claimed |
| US-20240091202-A1 | COMPOSITIONS FOR THE TREATMENT OF EBV ASSOCIATED DISEASES OR CONDITIONS | UNIVERSITÄT BASEL (CH) | 2024-03-21 | — | — | US | disclosed |
| EP-4301358-A2 | COMPOSITIONS FOR THE TREATMENT OF EBV ASSOCIATED DISEASES OR CONDITIONS | Universität Basel Vizerektorat Forschung (CH) | 2024-01-10 | — | — | EP | disclosed |
| CN-117295521-A | Compositions for treating EBV-associated diseases or conditions | 巴塞尔大学 | 2023-12-26 | — | — | CN | disclosed |
| WO-2022184930-A2 | COMPOSITIONS FOR THE TREATMENT OF EBV ASSOCIATED DISEASES OR CONDITIONS | UNIVERSITÄT BASEL (CH) | 2022-09-09 | — | — | WO | disclosed |
| EP-4052705-A1 | COMPOSITIONS FOR THE TREATMENT OF EBV ASSOCIATED DISEASES OR CONDITIONS | Universität Basel Vizerektorat Forschung (CH) | 2022-09-07 | — | — | EP | disclosed |
| CN-108264503-A | A kind of preparation method of 3- Indolylmaleimide compounds | 东华大学 | 2018-07-10 | — | — | CN | disclosed |
| CN-105153126-A | Preparation method of bisindolyl maleimide compounds | NAT UNIV DONG HWA | 2015-12-16 | — | — | CN | disclosed |
| CN-102702175-B | Preparation method of indole-3-succinimide | UNIV DONGHUA | 2014-08-13 | — | — | CN | disclosed |
| CN-102702175-B | Preparation method of indole-3-succinimide | UNIV DONGHUA | 2014-08-13 | — | — | CN | disclosed |
| CN-102702175-B | Preparation method of indole-3-succinimide | UNIV DONGHUA | 2014-08-13 | — | — | CN | disclosed |
| CN-102942560-A | Preparation method of 3-(2-methylindolyl-3-)pyrryl-2,5-dione | UNIV DONGHUA | 2013-02-27 | — | — | CN | disclosed |
| US-8377927-B2 | Compositions and methods for treatment of cancer | ARQULE, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| CN-102702175-A | Preparation method of indole-3-succinimide | UNIV DONGHUA | 2012-10-03 | — | — | CN | disclosed |
| CN-102702175-A | Preparation method of indole-3-succinimide | UNIV DONGHUA | 2012-10-03 | — | — | CN | disclosed |
| CN-102702175-A | Preparation method of indole-3-succinimide | UNIV DONGHUA | 2012-10-03 | — | — | CN | disclosed |
| US-20100221251-A1 | Compositions and Methods for Treatment of Cancer | ARQULE, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| EP-0477844-B1 | Indole compounds and their use | ORIENT CHEMICAL IND (JP) | 1997-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221251-A1 | Compositions and Methods for Treatment of Cancer | PDCD5, TP53, NUP205 | SMN1; SMN2 2087/4885RAB9A 2218/4885KDM4E 728/4885 |
| US-20240091202-A1 | COMPOSITIONS FOR THE TREATMENT OF EBV ASSOCIATED DISEASES OR CONDITIONS | IDO1, IDO2, MALT1 | SMN1; SMN2 4220/4885RAB9A 4159/4885KDM4E 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.