Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17386570 | 1.00 | RXRA (0.54) | RXRARXRBRXRGALDH1A1TSHR | |
| SCHEMBL17386552 | 0.88 | SCN9A (0.45) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL403300 | 0.88 | RXRA (0.58) | RXRARXRBRXRGALDH1A1TSHR | |
| SCHEMBL17664021 | 0.86 | RXRA (0.53) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL1924427 | 0.85 | SCN9A (0.43) | RXRARXRBRXRGALDH1A1TSHR | |
| SCHEMBL24860963 | 0.85 | NOTUM (0.60) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL402684 | 0.85 | RXRA (0.52) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL28035308 | 0.84 | RXRA (0.54) | RXRARXRBRXRGALDH1A1TSHR | |
| SCHEMBL29638900 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2ASCN9A | |
| SCHEMBL79042 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1KMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845490-B | 2-acylaminothiazole derivative or salt thereof | 旭飞药业股份有限公司 | 2023-03-28 | — | — | CN | disclosed |