SCHEMBL304417

SCHEMBL304417

O=C(NCl)N(Cl)C(=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
RAB9A P51151 1/20 0.42
DEPTOR Q8TB45 1/20 0.41
CES1 P23141 3/20 0.40
ALOX15 P16050 2/20 0.40
HPGD P15428 2/20 0.40
MAPK1 P28482 2/20 0.40
CYP3A4 P08684 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 2/20 0.40
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
CES2 O00748 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9849003 0.83 CES1 (0.50) TDP1SMN1; SMN2L3MBTL1RAB9ADEPTOR
SCHEMBL27481685 0.77 DEPTOR (0.44) TDP1SMN1; SMN2L3MBTL1RAB9ADEPTOR
SCHEMBL783891 0.73 CES1 (0.50) TDP1SMN1; SMN2L3MBTL1RAB9ADEPTOR
SCHEMBL29876664 0.73 CES1 (0.50) TDP1SMN1; SMN2L3MBTL1RAB9ADEPTOR
SCHEMBL27364743 0.72 BLM (0.46) TDP1SMN1; SMN2L3MBTL1RAB9ADEPTOR
SCHEMBL19875704 0.72 CES1 (0.48) TDP1SMN1; SMN2L3MBTL1RAB9ADEPTOR
SCHEMBL2068767 0.71 NPSR1 (0.43) TDP1SMN1; SMN2L3MBTL1RAB9AALOX15
SCHEMBL10441168 0.70 TDP1 (0.48) TDP1SMN1; SMN2L3MBTL1RAB9ADEPTOR
SCHEMBL28648683 0.70 CES1 (0.46) TDP1SMN1; SMN2L3MBTL1RAB9ADEPTOR
SCHEMBL3902478 0.70 HSD11B1 (0.52) SMN1; SMN2RAB9ADEPTORCES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112074589-B Dishwashing detergent formulations comprising polyaspartic acid and grafted polymers based on oligosaccharides and polysaccharides as film-forming inhibition additives 巴斯夫欧洲公司 2024-12-27 CN disclosed
EP-3788125-B1 DISHWASHING DETERGENT FORMULATIONS COMPRISING POLYASPARTIC ACID AND GRAFT POLYMERS BASED ON OLIGO- AND POLYSACCHARIDES AS FILM INHIBITING ADDITIVES BASF SE (DE) 2024-03-13 EP disclosed
US-11840680-B2 Dishwashing detergent formulations comprising polyaspartic acid and graft polymers based on oligo- and polysaccharides as film inhibiting additives BASF SE (DE) 2023-12-12 US disclosed
EP-3230344-B1 METHOD FOR THE PREPARATION OF POLYASPARTIC ACID BY MEANS OF PRE-CONDENSATE BASF SE (DE) 2023-01-04 EP disclosed
EP-3347405-B1 METHOD FOR THE PREPARATION OF POLYASPARTIC ACID UNDER REFLUX BASF SE (DE) 2022-11-09 EP disclosed
EP-4074813-A1 ALKALINE DETERGENT COMPOSITION CONTAINING A CARBOXYLIC ACID/POLYALKYLENE OXIDE COPOLYMER FOR HARD WATER SCALE CONTROL Ecolab USA Inc. (US) 2022-10-19 EP disclosed
EP-3055400-B1 ALKALINE DETERGENT COMPOSITION CONTAINING A CARBOXYLIC ACID/POLYALKYLENE OXIDE COPOLYMER FOR HARD WATER SCALE CONTROL ECOLAB USA INC (US) 2022-06-15 EP disclosed
EP-3055399-B1 ALKALINE DETERGENT COMPOSITION CONTAINING A CARBOXYLIC ACID TERPOLYMER FOR HARD WATER SCALE CONTROL ECOLAB USA INC (US) 2022-06-15 EP disclosed
US-11332700-B2 Use of branched polyesters based on citric acid as additive in washing compositions, cleaners, detergents or a formulation for water treatment BASF SE (DE) 2022-05-17 US disclosed
US-11214758-B2 Itaconic acid polymers and copolymers LUBRIZOL ADVANCED MATERIALS, INC. (US) 2022-01-04 US disclosed
US-20100160203-A1 CLEANING FORMULATIONS FOR MACHINE DISHWASHING COMPRISING HYDROPHILICALLY MODIFIED POLYCARBOXYLATES BASF SE (DE) 2010-06-24 US disclosed
US-20100144576-A1 DISH DETERGENT BK GIULINI GMBH (DE) 2010-06-10 US disclosed
CN-101631848-A Dish washing detergent LANXESS DEUTSCHLAND GMBH 2010-01-20 CN disclosed
US-7557074-B2 Cleaning formulations for dishcleaning machine containing hydrophobically modified polycarboxylate BASF AKTIENGESELLSCHAFT (DE) 2009-07-07 US disclosed
US-7410939-B2 Cleaning agent composition comprising polymers containing nitrogen BASF AKTIENGESELLSCHAFT (DE) 2008-08-12 US disclosed
US-20080188391-A1 Cleaning Formulations for Machine Dishwashing Comprising Hyrdophilically Modified Polycarboxylates BASF SE (DE) 2008-08-07 US disclosed
US-20070219110-A1 CLEANING FORMULATIONS FOR DISHCLEANING MACHINE CONTAINING HYDROPHOBICALLY MODIFIED POLYCARBOXYLATE BASF AKTIENGESELLSCHAFT (DE) 2007-09-20 US disclosed
US-20050032667-A1 Cleaning agent composition comprising polymers containing nitrogen BASF AKTIENGESELLSCHAFT (DE) 2005-02-10 US disclosed
US-20040072716-A1 Cleaner formulation that prevent the discoloration of plastic articles RECKITT BENCKISER N.V. (NL) 2004-04-15 US disclosed
US-20040058846-A1 Copolymers that prevent glass from corroding BASF AKTIENGESELLSCHAFT (DE) 2004-03-25 US disclosed