Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630702 | 0.86 | ALDH1A1 (0.41) | CES1CES2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL29876664 | 0.84 | CES1 (0.50) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL9849003 | 0.84 | CES1 (0.50) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL19875704 | 0.82 | CES1 (0.48) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL6561305 | 0.81 | CES1 (0.52) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL10441168 | 0.80 | TDP1 (0.48) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL3902478 | 0.80 | HSD11B1 (0.52) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL28648683 | 0.80 | CES1 (0.46) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL10990339 | 0.80 | CA2 (0.48) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL11145113 | 0.80 | CES1 (0.46) | CES1CES2ALDH1A1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694648-B1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER SAS (FR) | 2015-07-29 | — | — | EP | claimed |
| EP-1694649-B1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2014-01-22 | — | — | EP | claimed |
| US-8318777-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2012-11-27 | — | — | US | claimed |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2012-03-22 | — | — | US | claimed |
| US-8071629-B2 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-06 | — | — | US | claimed |
| US-8071627-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2011-12-06 | — | — | US | claimed |
| JP-4774043-B2 | — | — | 2011-09-14 | — | — | JP | claimed |
| US-7932396-B2 | 2-pyridinylcycloalkylbenzamide derivatives and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | claimed |
| CN-1898210-B | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER CROPSCIENCE SA | 2011-03-30 | — | — | CN | claimed |
| EP-2289880-A1 | 2-Pyridinylcyclopropylbenzamide fungicides | Bayer CropScience AG (DE) | 2011-03-02 | — | — | EP | claimed |
| WO-2005103006-A1 | 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2005-11-03 | — | — | WO | claimed |
| EP-1591442-A1 | 2-Pyridinycycloalkylbenzamide derivatives and their use as fungicides | Bayer CropScience S.A. (FR) | 2005-11-02 | — | — | EP | claimed |
| WO-2005058828-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE S.A. (FR) | 2005-06-30 | — | — | WO | claimed |
| WO-2005058833-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2005-06-30 | — | — | WO | claimed |
| EP-1548007-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | Bayer CropScience S.A. (FR) | 2005-06-29 | — | — | EP | claimed |
| WO-2001041763-A1 | TREATMENT OF ADDICTION DISORDERS | UNIVERSITY OF CINCINNATI (US) | 2001-06-14 | — | — | WO | claimed |
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | claimed |
| US-4116953-A | 2-PHENYL-3,1-BENZOXAZIN-4-ONES, PIGMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | claimed |
| US-4042591-A | PIGMENTS, DISPERSE DYES | SANDOZ LTD. (CH) | 1977-08-16 | — | — | US | claimed |
| US-3978039-A | POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP3A5 | CES1 366/4885CES2 103/4885ALDH1A1 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.