SCHEMBL9849003

SCHEMBL9849003

O=C(c1ccccc1)N(Cl)C(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.50
CES2 O00748 3/20 0.50
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
DEPTOR Q8TB45 1/20 0.48
MAPK1 P28482 2/20 0.46
TRPA1 O75762 1/20 0.46
GSK3B P49841 1/20 0.46
HIF1A Q16665 1/20 0.46
TDP1 Q9NUW8 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CYP3A4 P08684 2/20 0.46
MAPT P10636 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
POLB P06746 2/20 0.46
PARP1 P09874 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27481685 0.88 DEPTOR (0.44) CES1CES2ALDH1A1TSHRDAO
SCHEMBL10441168 0.85 TDP1 (0.48) CES1CES2ALDH1A1TSHRDAO
SCHEMBL29876664 0.84 CES1 (0.50) CES1CES2ALDH1A1TSHRDAO
SCHEMBL783891 0.84 CES1 (0.50) CES1CES2ALDH1A1TSHRDAO
SCHEMBL27364743 0.83 BLM (0.46) CES1CES2ALDH1A1TSHRDAO
SCHEMBL304417 0.83 TDP1 (0.42) CES1CES2ALDH1A1TSHRDAO
SCHEMBL1949098 0.82 TDP1 (0.56) CES1CES2ALDH1A1DEPTORHIF1A
SCHEMBL19875704 0.82 CES1 (0.48) CES1CES2ALDH1A1TSHRDAO
SCHEMBL1948739 0.81 CES1 (0.66) CES1CES2ALDH1A1TSHRMAPK1
SCHEMBL10990339 0.80 CA2 (0.48) CES1CES2ALDH1A1TSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458197-A2 Use of N-haloamides as photoinitiators for free-radical polymerizations MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1991-11-27 EP disclosed