Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10162230 | 0.79 | NPC1 (0.45) | SMN1; SMN2LMNAPOLBRAB9ANPC1 | |
| SCHEMBL7566383 | 0.78 | KDM4E (0.42) | ALDH1A1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL7146697 | 0.78 | FBP1 (0.47) | ALDH1A1SMN1; SMN2LMNAPOLBRAB9A | |
| SCHEMBL15739862 | 0.78 | RAB9A (0.42) | ALDH1A1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL9435348 | 0.78 | GAA (0.47) | ALDH1A1SMN1; SMN2LMNAPOLBRAB9A | |
| SCHEMBL11238301 | 0.78 | PDPK1 (0.42) | ALDH1A1SMN1; SMN2LMNAPOLBRAB9A | |
| SCHEMBL28491322 | 0.78 | NOTUM (0.41) | ALDH1A1LMNARAB9ANPC1NOTUM | |
| SCHEMBL12925903 | 0.78 | RAB9A (0.51) | ALDH1A1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL30441982 | 0.78 | NOTUM (0.41) | ALDH1A1LMNARAB9ANPC1NOTUM | |
| SCHEMBL28156677 | 0.78 | MAPT (0.51) | ALDH1A1SMN1; SMN2POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231657-A1 | BIARYL SUBSTITUTED AZABICYCLIC ALKANE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY MODULATORS | Abbott Laboratories (US) | 2010-09-29 | — | — | EP | claimed |
| WO-2009067579-A1 | BIARYL SUBSTITUTED AZABICYCLIC ALKANE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY MODULATORS | ABBOTT LABORATORIES (US) | 2009-05-28 | — | — | WO | claimed |
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
| CN-111995620-B | Preparation method of 1,3, 4-thiadiazole compound and compound prepared by same | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-111995620-A | Preparation method of 1,3, 4-thiadiazole compound and compound prepared by same | 重庆医科大学 | 2020-11-27 | — | — | CN | disclosed |
| US-7867980-B2 | Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CGAS, TDP1, CYP11B2 | ALDH1A1 987/4885SMN1; SMN2 1142/4885LMNA 1585/4885 |
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | SIRT6, LAS1L, MRPS18A | ALDH1A1 3217/4885SMN1; SMN2 1070/4885LMNA 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.