Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704708 | 0.86 | KDM4E (0.62) | KDM4EPOLBATMALDH1A1GLA | |
| Formic Acid SCHEMBL5396593 | 0.79 | KDM4E (0.55) | KDM4EPOLBATMALDH1A1GLA | |
| SCHEMBL1896087 | 0.78 | KDM4E (0.62) | KDM4EPOLBATMALDH1A1GLA | |
| SCHEMBL8628627 | 0.77 | POLB (0.67) | KDM4EPOLBATMALDH1A1GAA | |
| SCHEMBL6964053 | 0.75 | KDM4E (0.64) | KDM4EPOLBATMALDH1A1GLA | |
| SCHEMBL31087257 | 0.75 | POLB (0.64) | KDM4EPOLBATMALDH1A1KMT2A | |
| N-Methylanthranilic Acid SCHEMBL29381752 | 0.75 | KDM4E (0.64) | KDM4EPOLBATMALDH1A1KMT2A | |
| N-Methylanthranilic Acid SCHEMBL130356 | 0.75 | KDM4E (0.64) | KDM4EPOLBATMALDH1A1KMT2A | |
| SCHEMBL848499 | 0.75 | POLB (0.64) | KDM4EPOLBATMALDH1A1KMT2A | |
| SCHEMBL960781 | 0.74 | KDM4E (0.58) | KDM4EPOLBATMALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734983-A2 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | Engrail Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025010255-A2 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | ENGRAIL THERAPEUTICS, INC. (US) | 2025-01-09 | — | — | WO | disclosed |
| EP-4460292-A1 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | Engrail Therapeutics, Inc. (US) | 2024-11-13 | — | — | EP | disclosed |
| EP-4460490-A1 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | Engrail Therapeutics, Inc. (US) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023130119-A1 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | ENGRAIL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023130117-A1 | DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF | ENGRAIL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |