Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628627 | 0.84 | POLB (0.67) | KDM4EPOLBATMKDM4CALDH1A1 | |
| SCHEMBL848499 | 0.82 | POLB (0.64) | KDM4EPOLBATMALDH1A1RECQL | |
| N-Methylanthranilic Acid SCHEMBL29381752 | 0.82 | KDM4E (0.64) | KDM4EPOLBATMKDM4CALDH1A1 | |
| SCHEMBL31087257 | 0.82 | POLB (0.64) | KDM4EPOLBATMALDH1A1RECQL | |
| N-Methylanthranilic Acid SCHEMBL130356 | 0.82 | KDM4E (0.64) | KDM4EPOLBATMKDM4CALDH1A1 | |
| SCHEMBL16523772 | 0.80 | KDM4E (0.62) | KDM4EPOLBATMKDM4CALDH1A1 | |
| Hydrochloric Acid SCHEMBL15974089 | 0.80 | POLB (0.62) | KDM4EPOLBATMALDH1A1RECQL | |
| N-Methylanthranilic Acid SCHEMBL10796607 | 0.80 | KDM4E (0.62) | KDM4EPOLBATMKDM4CALDH1A1 | |
| SCHEMBL2061071 | 0.80 | POLB (0.62) | KDM4EPOLBATMALDH1A1RECQL | |
| N-Methylanthranilic Acid SCHEMBL9787433 | 0.80 | KDM4E (0.62) | KDM4EPOLBATMKDM4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |