Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26072673 | 1.00 | GPR119 (0.42) | GPR119PTGS2KDRMAPK14STAT3 | |
| SCHEMBL26072118 | 0.94 | GPR119 (0.42) | GPR119PTGS2KDRMAPK14STAT3 | |
| SCHEMBL29396269 | 0.94 | GPR119 (0.42) | GPR119PTGS2KDRMAPK14STAT3 | |
| SCHEMBL26072716 | 0.91 | GPR119 (0.43) | GPR119PTGS2STAT3 | |
| SCHEMBL29395748 | 0.91 | GPR119 (0.43) | GPR119PTGS2STAT3 | |
| SCHEMBL26072047 | 0.85 | GPR119 (0.45) | GPR119STAT3 | |
| SCHEMBL31576220 | 0.85 | GPR119 (0.45) | GPR119STAT3 | |
| SCHEMBL31576213 | 0.77 | CCR2 (0.38) | PTGS2STAT3 | |
| SCHEMBL26072351 | 0.77 | CCR2 (0.38) | PTGS2STAT3 | |
| SCHEMBL31576221 | 0.76 | GPR119 (0.44) | GPR119PTGS2KDRMAPK14PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200298-B1 | 1H-PYRROLO[3,2-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS | BRISTOL MYERS SQUIBB CO (US) | 2025-05-21 | — | — | EP | claimed |
| CN-115867549-A | 1H-pyrrolo [3,2-c ] pyridine and 1H-pyrrolo [2,3-c ] pyridine derivatives as TLR9 inhibitors for the treatment of fibrosis | 百时美施贵宝公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115867549-A | 1H-pyrrolo [3,2-c ] pyridine and 1H-pyrrolo [2,3-c ] pyridine derivatives as TLR9 inhibitors for the treatment of fibrosis | 百时美施贵宝公司 | 2023-03-28 | — | — | CN | disclosed |