SCHEMBL31576220

SCHEMBL31576220

CC(C)(O)CCN1CCN(Cc2ccc(-c3cc4c(cn3)cc(-c3ccc(S(C)(=O)=O)cc3)n4C3CC3)cc2)CC1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 4/20 0.45
▸ CCR2 P41597 15/20 0.43
▸ STAT3 P40763 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26072047 1.00 GPR119 (0.45) GPR119CCR2STAT3
SCHEMBL26072716 0.92 GPR119 (0.43) GPR119CCR2STAT3
SCHEMBL29395748 0.92 GPR119 (0.43) GPR119CCR2STAT3
SCHEMBL29396269 0.87 GPR119 (0.42) GPR119STAT3
SCHEMBL26072118 0.87 GPR119 (0.42) GPR119STAT3
SCHEMBL29395772 0.87 CCR2 (0.44) CCR2
SCHEMBL26072701 0.87 CCR2 (0.44) CCR2
SCHEMBL30442239 0.85 GPR119 (0.42) GPR119STAT3
SCHEMBL26072673 0.85 GPR119 (0.42) GPR119STAT3
SCHEMBL31576213 0.78 CCR2 (0.38) CCR2STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4200298-B1 1H-PYRROLO[3,2-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS BRISTOL MYERS SQUIBB CO (US) 2025-05-21 — — EP claimed
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