Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | TYK2 | P29597 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25388907 | 1.00 | MAPK10 (0.55) | MAPK10TNNI3KMAPTALDH1A1NPC1 | |
| SCHEMBL29501419 | 0.89 | MAPK10 (0.55) | MAPK10TNNI3KMAPTALDH1A1NPC1 | |
| SCHEMBL25389479 | 0.89 | MAPK10 (0.55) | MAPK10TNNI3KMAPTALDH1A1NPC1 | |
| SCHEMBL3226915 | 0.84 | S1PR1 (0.61) | MAPK10TNNI3KMAPTALDH1A1NPC1 | |
| SCHEMBL3227948 | 0.81 | S1PR1 (0.61) | MAPK10TNNI3KMAPTALDH1A1NPC1 | |
| SCHEMBL3225993 | 0.80 | MEN1 (0.57) | MAPK10TNNI3KMAPTALDH1A1NPC1 | |
| SCHEMBL23412580 | 0.79 | MAPT (0.55) | MAPK10MAPTALDH1A1NPC1GAA | |
| SCHEMBL29887169 | 0.79 | MAPT (0.55) | MAPK10MAPTALDH1A1NPC1GAA | |
| SCHEMBL13321937 | 0.79 | MAPK10 (0.61) | MAPK10TNNI3KMAPTALDH1A1NPC1 | |
| SCHEMBL11939655 | 0.78 | MAPK10 (0.49) | MAPK10TNNI3KMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113626-A | Compound with anti-tumor activity and application thereof | 上海翊石医药科技有限公司 | 2023-05-12 | — | — | CN | disclosed |