Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.55 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.51 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.49 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443993 | 0.89 | PSMB9 (0.54) | OPRM1OPRD1KEAP1PSMB9CALCRL | |
| SCHEMBL30186556 | 0.86 | CALCRL (0.55) | NMUR2NMUR1OPRM1OPRD1KEAP1 | |
| SCHEMBL31323239 | 0.85 | CALCRL (0.56) | NMUR2NMUR1OPRM1OPRD1KEAP1 | |
| Thymoctonan SCHEMBL1230532 | 0.84 | REN (0.52) | OPRM1OPRD1KEAP1CALCRLRAMP1 | |
| Thymoctonan SCHEMBL15532000 | 0.84 | REN (0.52) | OPRM1OPRD1KEAP1CALCRLRAMP1 | |
| SCHEMBL30289679 | 0.84 | SLC6A2 (0.58) | OPRM1OPRD1PSMB9CALCRLRAMP1 | |
| SCHEMBL29884359 | 0.83 | OPRM1 (0.55) | NMUR2OPRM1OPRD1KEAP1PSMB9 | |
| SCHEMBL29579416 | 0.83 | CALCRL (0.54) | OPRM1OPRD1PSMB9CALCRLRAMP1 | |
| SCHEMBL30259604 | 0.83 | REN (0.53) | OPRM1OPRD1CALCRLRAMP1REN | |
| SCHEMBL29579716 | 0.83 | CALCRL (0.61) | OPRM1OPRD1PSMB9CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11833185-B2 | Anti-neurodegenerative therapeutic, method of manufacture, and use | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-12-05 | — | — | US | disclosed |
| EP-3664831-B1 | ANTI-NEURODEGENERATIVE THERAPEUTIC AND USE | UNIV KENTUCKY RES FOUND (US) | 2023-06-14 | — | — | EP | disclosed |