Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | PNP | P00491 | 3/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708640 | 0.93 | ALDH1A1 (0.38) | ALDH1A1KDM4ERXFP1HPRT1CDK2 | |
| SCHEMBL3054589 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KDM4ERXFP1HPRT1CDK2 | |
| SCHEMBL9617743 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4ERXFP1HPRT1CDK2 | |
| SCHEMBL460357 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4ERXFP1CDK2 | |
| SCHEMBL9515925 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4ERXFP1CDK2PAK1 | |
| SCHEMBL4969622 | 0.72 | KDM4E (0.38) | ALDH1A1KDM4ERXFP1HPRT1CDK2 | |
| SCHEMBL8710364 | 0.72 | HPRT1 (0.33) | HPRT1 | |
| SCHEMBL28215939 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4ERXFP1CDK2PAK1 | |
| SCHEMBL31618832 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4ERXFP1CDK2PAK1 | |
| SCHEMBL5482507 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4ERXFP1CDK2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754718-B2 | Antiviral helioxanthin analogs | YALE UNIVERSITY (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | YALE UNIVERSITY (US) | 2008-07-10 | — | — | US | disclosed |
| WO-2005107742-A1 | NOVEL ANTIVIRAL HELIOXANTHIN ANALOGS | YALE UNIVERSITY (US) | 2005-11-17 | — | — | WO | disclosed |
| US-6306899-B1 | VIRICIDES | YALE UNIVERSITY | 2001-10-23 | — | — | US | disclosed |
| EP-1107961-A1 | INHIBITION AND TREATMENT OF HEPATITIS B VIRUS AND FLAVIVIRUS BY HELIOXANTHIN AND ITS ANALOGS | YALE UNIVERSITY (US) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000010991-A1 | INHIBITION AND TREATMENT OF HEPATITIS B VIRUS AND FLAVIVIRUS BY HELIOXANTHIN AND ITS ANALOGS | YALE UNIVERSITY (US) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | HAVCR2, ZC3HAV1, DHX35 | ALDH1A1 1351/4885KDM4E 1857/4885RXFP1 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.