SCHEMBL30444571

SCHEMBL30444571

CC[Si](CC)(CC)Cc1cccc2c1cc([Si](CC)(CC)CC)n2C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPEPPS P55786 1/20 0.34
GPR3 P46089 1/20 0.32
LMNA P02545 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17504849 1.00 NPEPPS (0.34) NPEPPSGPR3LMNAL3MBTL1
SCHEMBL19557282 0.86 NPEPPS (0.42) NPEPPSGPR3LMNAL3MBTL1
SCHEMBL17504843 0.78 ALKBH5 (0.42) NPEPPSGPR3LMNAL3MBTL1
SCHEMBL29509065 0.78 ALKBH5 (0.42) NPEPPSGPR3LMNAL3MBTL1
SCHEMBL12278274 0.74 MAPT (0.36) GPR3L3MBTL1
SCHEMBL30444626 0.69 KMT2A (0.46)
SCHEMBL15639678 0.69 KMT2A (0.46)
SCHEMBL28176244 0.69
SCHEMBL17504848 0.66 RPS6KA5 (0.39) LMNAL3MBTL1
SCHEMBL12279306 0.66 DHFR (0.33) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111253424-B Silylation of aromatic heterocycles over earth-rich transition metal-free catalysts 加州理工学院 2023-06-20 CN disclosed