Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15638026 | 1.00 | SLC6A4 (0.44) | SLC6A4RIPK1SLC6A2LTA4HHRH1 | |
| SCHEMBL30114552 | 0.78 | CA1 (0.50) | TSHRL3MBTL1ALDH1A1MAPK1HTT | |
| SCHEMBL24631916 | 0.78 | LTA4H (0.46) | SLC6A4RIPK1SLC6A2LTA4HHRH1 | |
| SCHEMBL15637986 | 0.78 | CA1 (0.50) | TSHRL3MBTL1ALDH1A1MAPK1HTT | |
| SCHEMBL4555692 | 0.77 | RIPK1 (0.41) | SLC6A4RIPK1SLC6A2LTA4HHRH1 | |
| SCHEMBL28924088 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL18096790 | 0.74 | ALDH1A1 (0.47) | SLC6A4RIPK1SLC6A2LTA4HHRH1 | |
| SCHEMBL3091248 | 0.74 | HTT (0.47) | SLC6A4RIPK1SLC6A2LTA4HHRH1 | |
| SCHEMBL18096793 | 0.74 | LTA4H (0.46) | SLC6A4RIPK1SLC6A2LTA4HHRH1 | |
| SCHEMBL18096763 | 0.74 | LTA4H (0.46) | SLC6A4RIPK1SLC6A2LTA4HHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253424-B | Silylation of aromatic heterocycles over earth-rich transition metal-free catalysts | 加州理工学院 | 2023-06-20 | — | — | CN | disclosed |