Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25464698 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22813353 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25174808 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2146868 | 0.73 | ALDH1A1 (0.39) | ALDH1A1LMNACYP1A2MEN1KMT2A | |
| SCHEMBL14191432 | 0.69 | LMNA (0.46) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1846229 | 0.68 | LMNA (0.51) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17033019 | 0.68 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL29986630 | 0.67 | ALDH1A1 (0.38) | ALDH1A1LMNACA12CA9MEN1 | |
| SCHEMBL27189958 | 0.67 | ALDH1A1 (0.38) | ALDH1A1LMNACA12CA9MEN1 | |
| SCHEMBL29529168 | 0.66 | CASP3 (0.58) | ALDH1A1CA12CA9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408847-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023049887-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | WO | disclosed |