SCHEMBL30444732

SCHEMBL30444732

Clc1cccc(-c2cc(Cl)c(Cl)c(Cl)c2Cl)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.48
CYP3A4 P08684 2/20 0.43
NOTUM Q6P988 2/20 0.40
IDO1 P14902 1/20 0.40
NUDT1 P36639 4/20 0.40
TSHR P16473 2/20 0.39
CYP2D6 P10635 1/20 0.38
MAOA P21397 1/20 0.38
MAPK1 P28482 1/20 0.38
ADRA1A P35348 1/20 0.38
SCN4A P35499 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
PDE3A Q14432 1/20 0.38
SCN5A Q14524 1/20 0.38
SCN9A Q15858 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
SCN10A Q9Y5Y9 1/20 0.38
PNMT P11086 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453591 1.00 AHR (0.48) AHRCYP3A4NOTUMIDO1NUDT1
SCHEMBL4459798 0.84 AHR (0.50) AHRCYP3A4IDO1TSHRMAPK1
SCHEMBL29450677 0.83 AHR (0.62) AHRCYP3A4TSHRMAPK1HSP90AA1
SCHEMBL811508 0.83 AHR (0.50) AHRCYP3A4NOTUMIDO1NUDT1
SCHEMBL2229300 0.83 AHR (0.62) AHRCYP3A4TSHRMAPK1HSP90AA1
SCHEMBL440943 0.83 TSHR (0.52) CYP3A4NOTUMIDO1NUDT1TSHR
SCHEMBL4456505 0.82 ALDH1A1 (0.48) AHRNOTUMIDO1NUDT1TSHR
SCHEMBL30034845 0.80 CYP3A4 (0.67) AHRCYP3A4TSHRMAPK1HSP90AA1
SCHEMBL2230314 0.80 CYP3A4 (0.67) AHRCYP3A4TSHRMAPK1HSP90AA1
SCHEMBL4459297 0.79 AHR (0.50) AHRCYP3A4TSHRPNMTHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-116392146-A Implantable device 上海阶梯医疗科技有限公司 2023-07-07 CN disclosed
CN-116369927-A Method for forming implanted device 上海阶梯医疗科技有限公司 2023-07-04 CN disclosed