SCHEMBL440943

SCHEMBL440943

Clc1cccc(-c2cccc(Cl)c2Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
NOTUM Q6P988 2/20 0.50
IDO1 P14902 1/20 0.50
NUDT1 P36639 2/20 0.48
PNMT P11086 2/20 0.48
CYP2A6 P11509 2/20 0.47
CYP1A2 P05177 2/20 0.47
LMNA P02545 1/20 0.47
CYP2D6 P10635 2/20 0.47
MAOA P21397 1/20 0.47
MAPK1 P28482 1/20 0.47
ADRA1A P35348 1/20 0.47
SCN4A P35499 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
PDE3A Q14432 1/20 0.47
SCN5A Q14524 1/20 0.47
SCN9A Q15858 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL381601 0.91 CYP2A6 (0.52) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL29385608 0.91 CYP2A6 (0.52) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL811508 0.89 AHR (0.50) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL4456270 0.85 TSHR (0.46) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL4450490 0.84 AHR (0.57) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL2466764 0.84 TAAR1 (0.42) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL2495859 0.84 NUDT1 (0.49) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL2769483 0.84 TSHR (0.52) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL29624838 0.83 TSHR (0.44) TSHRNOTUMIDO1NUDT1PNMT
SCHEMBL2229304 0.83 TSHR (0.44) TSHRNOTUMIDO1NUDT1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119619489-A Homogeneous enzyme immunoassay system based on click chemistry coupling technology and preparation method and application thereof 苏州博源医疗科技有限公司 2025-03-14 CN claimed
CN-119361834-A Electrolyte and battery and electricity utilization device containing same 浙江大学 2025-01-24 CN claimed
CN-118389643-A Biological sensing environment detection platform for detecting small molecules sensitively based on fluorescent RNA aptamer logic gate 湘潭大学 2024-07-26 CN claimed
CN-113773998-B PCBs composite degrading microbial inoculum and application thereof 广东海洋大学 2023-03-21 CN claimed
CN-111665313-B Method for determining polychlorinated biphenyl compounds in aquatic products 孟祥龙 2022-10-11 CN claimed
CN-111235077-B Composite biological agent for repairing polychlorinated biphenyl polluted soil 河南国佑生态修复技术有限公司 2022-09-16 CN claimed
CN-114196618-A Exposure system of organic flame retardant to human respiratory tract cells and preparation method and application thereof 广东工业大学 2022-03-18 CN claimed
CN-109762776-B Microbial agent for improving soil quality, preparation method and application 中国环境科学研究院 2022-02-01 CN claimed
CN-109868243-B Microbial agent for accelerating soil organic matter pollution remediation, preparation method and application thereof 中国环境科学研究院 2022-02-01 CN claimed
CN-113945650-A Method for simultaneously analyzing persistent organic pollutants in grains 国家粮食和物资储备局科学研究院 2022-01-18 CN claimed
US-20060281961-A1 Functional transition metal silicates KANUMURU RAHUL RAJU (IN) 2006-12-14 US claimed
US-6544773-B1 For degrading different congeners namely coplanar, sterically hindered and other chlorobiphenyls COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-04-08 US claimed
US-20030054538-A1 Microbial process for degradation of PCBs in clophen A-50 using a novel marine microorganism, pseudomonas CH07 SARKAR ANUPAM (IN) 2003-03-20 US claimed
CN-1034243-C Marking with tetrachloro-diphenyl urea for rat luteinizing hormone and prolactin TIANJIN FAMILY PLAN INST (CN) 1997-03-12 CN claimed
EP-0558997-B1 Process for reducing the halogen-content of polyhalogenated aromatics BAYER AG (DE) 1995-11-22 EP claimed
US-5292975-A Platinum metal catalyst BAYER AKTIENGESELLSCHAFT (DE) 1994-03-08 US claimed
CN-1063941-A The marking with tetrachloro-diphenyl of rat luteinizing hormone and prolactin TIANJIN FAMILY PLAN INST (CN) 1992-08-26 CN claimed
US-4490266-A Process for the preparation of liquids of low inflammability and high viscosity index and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1984-12-25 US claimed
US-4200698-A BROMO BUTADIENE POLYMER, CHLOROCARBON, EPOXIDIZED CYCLOOLEFIN, POLYAMINE OR POLYAMIDE MICAFIL, AG (CH) 1980-04-29 US claimed
US-4067990-A SOLUTION OF A PHENYL N-METHYL CARBAMATE AIRWICK INDUSTRIES, INC. (US) 1978-01-10 US claimed