SCHEMBL4456505

SCHEMBL4456505

Clc1cc(Cl)c(Cl)c(-c2cccc(Cl)c2Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
NOTUM Q6P988 2/20 0.40
IDO1 P14902 1/20 0.40
NUDT1 P36639 4/20 0.40
TSHR P16473 2/20 0.39
AHR P35869 2/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
P2RX7 Q99572 1/20 0.39
SCN2A Q99250 2/20 0.38
CYP2D6 P10635 1/20 0.38
MAOA P21397 1/20 0.38
MAPK1 P28482 1/20 0.38
ADRA1A P35348 1/20 0.38
SCN4A P35499 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
PDE3A Q14432 1/20 0.38
SCN5A Q14524 1/20 0.38
SCN9A Q15858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29765253 0.86 ALDH1A1 (0.48) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL4453348 0.86 ALDH1A1 (0.48) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL4456396 0.84 ALDH1A1 (0.50) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL4456481 0.84 ALDH1A1 (0.43) ALDH1A1NOTUMIDO1NUDT1TSHR
SCHEMBL440943 0.83 TSHR (0.52) NOTUMIDO1NUDT1TSHRP2RX7
SCHEMBL2930780 0.83 ALDH1A1 (0.69) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL30444732 0.82 AHR (0.48) NOTUMIDO1NUDT1TSHRAHR
SCHEMBL4453591 0.82 AHR (0.48) NOTUMIDO1NUDT1TSHRAHR
SCHEMBL4450365 0.82 AHR (0.56) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL4450231 0.80 P2RX7 (0.44) ALDH1A1NOTUMIDO1NUDT1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
WO-2023051123-A1 ANTENNA SYSTEM AND ELECTRONIC DEVICE 华为技术有限公司 2023-04-06 WO disclosed
CN-115882219-A Antenna system and electronic equipment 华为技术有限公司 2023-03-31 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed