Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249203 | 0.88 | MAPT (0.42) | DGAT1MEN1KMT2AMAPT | |
| SCHEMBL19284539 | 0.86 | HSP90AB1 (0.34) | DGAT1MAOBPDE10AMAPTTP53 | |
| SCHEMBL17258588 | 0.85 | L3MBTL1 (0.33) | DGAT1MAOBALOX5APFEN1MAPT | |
| SCHEMBL2471286 | 0.83 | KDM4E (0.41) | DGAT1MAOBAPP | |
| SCHEMBL23043051 | 0.83 | DGAT1 (0.38) | DGAT1MAOBALOX5APFEN1MEN1 | |
| SCHEMBL5251130 | 0.82 | DGAT1 (0.31) | DGAT1MAOB | |
| SCHEMBL5247767 | 0.82 | HTR1A (0.34) | DGAT1MAOBAPP | |
| SCHEMBL17595534 | 0.81 | DGAT1 (0.42) | DGAT1MAOBMEN1KMT2AMAPT | |
| SCHEMBL30467939 | 0.80 | DGAT1 (0.34) | DGAT1ALOX5APFEN1PDE10AMAPT | |
| SCHEMBL25561687 | 0.79 | DGAT1 (0.33) | DGAT1MAOBALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265458-A | Benzothiophene derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-20 | — | — | CN | disclosed |