SCHEMBL30445678

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	SLC6A2	P23975	1/20	0.60

▸	AGTR2	P50052	4/20	0.59

▸	AGTR1	P30556	3/20	0.59

▸	REN	P00797	2/20	0.58

▸	NTSR2	O95665	7/20	0.57

▸	NTSR1	P30989	7/20	0.57

▸	SORT1	Q99523	6/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29548836	1.00	SLC6A2 (0.60)	SLC6A2AGTR2AGTR1RENNTSR2
SCHEMBL30446840	0.95	NTSR2 (0.54)	AGTR2AGTR1NTSR2NTSR1SORT1
SCHEMBL30446282	0.95	NTSR2 (0.54)	AGTR2AGTR1NTSR2NTSR1SORT1
SCHEMBL30445757	0.92	SLC6A2 (0.62)	SLC6A2REN
SCHEMBL29416554	0.92	SLC6A2 (0.64)	SLC6A2REN
SCHEMBL28659771	0.88	OPRM1 (0.68)	SLC6A2
SCHEMBL28659786	0.88	OPRM1 (0.68)	SLC6A2
SCHEMBL29571594	0.87	NTSR1 (0.62)	NTSR2NTSR1SORT1
SCHEMBL29531376	0.87	SLC6A2 (0.72)	SLC6A2
SCHEMBL29530548	0.87	SLC6A2 (0.72)	SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20250009853-A1	MUTANT ACE2 PROTEINS AND METHODS OF USING SAME	WISCONSIN ALUMNI RESEARCH FOUNDATION (US)	2025-01-09	—	—	US	disclosed
WO-2023102156-A1	MUTANT ACE2 PROTEINS AND METHODS OF USING SAME	WISCONSIN ALUMNI RESEARCH FOUNDATION (US)	2023-06-08	—	—	WO	disclosed