Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR2 | O95665 | 12/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 12/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 11/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30446282 | 1.00 | NTSR2 (0.54) | NTSR2NTSR1SORT1AGTR1AGTR2 | |
| SCHEMBL29548836 | 0.95 | SLC6A2 (0.60) | NTSR2NTSR1SORT1AGTR1AGTR2 | |
| SCHEMBL30445678 | 0.95 | SLC6A2 (0.60) | NTSR2NTSR1SORT1AGTR1AGTR2 | |
| SCHEMBL30050570 | 0.92 | OPRM1 (0.54) | — | |
| SCHEMBL29416554 | 0.90 | SLC6A2 (0.64) | — | |
| SCHEMBL30304785 | 0.88 | OPRM1 (0.53) | — | |
| SCHEMBL29571594 | 0.88 | NTSR1 (0.62) | NTSR2NTSR1SORT1 | |
| SCHEMBL30690391 | 0.87 | SLC6A2 (0.59) | AGTR1AGTR2 | |
| SCHEMBL28659786 | 0.85 | OPRM1 (0.68) | — | |
| SCHEMBL29630467 | 0.85 | SLC6A2 (0.61) | NTSR2NTSR1SORT1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009853-A1 | MUTANT ACE2 PROTEINS AND METHODS OF USING SAME | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-01-09 | — | — | US | disclosed |
| WO-2023102156-A1 | MUTANT ACE2 PROTEINS AND METHODS OF USING SAME | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-06-08 | — | — | WO | disclosed |